A complex disorder of carbohydrate, fat, and protein metabolism that is primarily due to lack of insulin secretion by the beta cells of the pancreas or of defects of the insulin receptors
Effect of Periodontal Disease on Diabetes Mellitus
The inflamed periodontium is highly vascular, and the ulcerated pocket epithelium may serve as a portal to the systemic circulation for bacterial products and locally produced inflammatory mediators
Any event in which environmental demands, internal demands or both tax or exceed the adaptive resources of an individual, social system or tissue system